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Primary Examiner: Trousof, Natalie
Assistant Examiner:
Attorney: Burgess, Dinklage & Sprung

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Title: 4-Hydroxy-benzimidazole compounds and therapeutic compositions

Abstract: New 4-hydroxy-benzimidazole compounds of the formula: ##EQU1## wherein R.sub.1 is straight-chained or branched alkyl and R.sub.2 is hydrogen atom or lower alkyl And the pharmacologically compatible salts thereof; are outstandingly effective in the treatment and prophylaxis of cardiac and circulatory diseases, and provide substantially greater margins of safety than prior art adrenergic .beta.-receptor inhibitors.

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Inventors: Fauland, Erich (Mannheim-Gartenstadt, DT)
Kampe, Wolfgang (Heddesheim, DT)
Thiel, Max (Mannheim, DT)
Bartsch, Wolfgang (Viernheim, DT)
Schaumann, Wolfgang (Heidelberg, DT)

Application Number: 585645
Filing Date: 1975-06-10
Publication_date: 1976-09-21
Assignee: Boehringer Mannheim G.m.b.H. (Mannheim, DT)
Primary Class(es): 514/394 548/304.4, 564/350
Other Classes:
US Patent Ref:
Other Refs: Other References: kasuya et al., Chem. Abst. 1973, vol. 79, No. 137129z.
Troxler, Chem. Abst. 1969, vol. 71, No. 70493c.