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Title:
Anti-inflammatory steroid
Abstract:
The disclosure covers the preparation of the compound, 6.alpha.,9.alpha.-difluoro-11.beta.,17,21-trihydroxy-16.beta.-methylpregna -1,4-diene-3,20-dione 17.alpha.,21-diacetate, (1) and methods and formulations for its anti-inflammatory use topically, orally and parenterally.
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Inventors:
Ayer, Donald E. (Kalamazoo, MI, US) Schlagel, Carl A. (Kalamazoo, MI, US) Flynn, Gordon L. (Ann Arbor, MI, US)
Application Number:
579177
Filing Date: 1975-05-20 Publication_date: 1976-09-14 Assignee:
The Upjohn Company (Kalamazoo, MI)
Primary Class(es):
514/171
514/180, 552/573, 552/593, 552/594, 552/595
Other Classes:
US Patent Ref:
| 3557158 | Jan, 1971 | Lincoln et al. | 260/397. | | 3691214 | Sep, 1972 | Ercoli et al. | 260/397. |
Other Refs:
Primary Examiner:
Roberts, Elbert L.
Assistant Examiner:
Attorney:
Stein; Bruce, Kekich; John
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