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Primary Examiner: Goldberg, Jerome D.
Assistant Examiner:
Attorney: Weigman; Joseph Martin

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Title: Method of viral chemoprophylaxis and compounds therefor

Abstract: It has been found that compounds having a stereochemically unencumbered access to a nitrogen-nitrogen bond have antiviral activity in extremely low dose ranges. Hydrazine, hydrazine derivatives and related compounds have been found to be active in protecting animals against disease caused by both DNA and RNA type viruses at doses of about 250 picograms to 250 micrograms per kilogram of host body weight.


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Inventors: Hegarty, Charles Paul (Radnor, PA, US)
Pietryk, Helen C. (Havertown, PA, US)

Application Number: 530888
Filing Date: 1974-12-09
Publication_date: 1976-09-14
Assignee: American Home Products Corporation (New York, NY)
Primary Class(es): 424/600 424/719, 514/614
Other Classes:
US Patent Ref:
Other Refs: Other References: chemical Abstracts 61:13766a (1964).