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Primary Examiner: Rosen, Sam
Assistant Examiner:
Attorney: Ellis; W. Garrettson, Altman; Louis

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Title: Methods of dissolving blood clots and the like with streptokinase chemically bonded to a carbohydrate matrix

Abstract: One part by weight of streptokinase is chemically bonded to one to five hundred parts by weight of a carbohydrate, to form a material which has improved stability compared with free streptokinase.


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Inventors: Ginger, Leonard George (Glenview, IL, US)
Mather, Adaline Nicoles (Evanston, IL, US)

Application Number: 185423
Filing Date: 1971-09-30
Publication_date: 1976-09-14
Assignee: Baxter Laboratories, Inc. (Deerfield, IL)
Primary Class(es): 424/94.3 424/94.64, 514/54, 514/57, 514/58, 514/59, 514/60, 514/822
Other Classes:
US Patent Ref:
3226304Dec, 1965Siiteri et al.424/94.

Other Refs: 1,815,332
Jul, 1969DT
Other References: Steinbuch et al., Bibliotheca haematologica, No. 19, pp. 169-173, 1962.
Axen et al., Nature, vol. 214, pp. 1302-1304, June 1967.