Title: Anti-allergic-3-carboxy-isocoumarin compositions and methods of use

Abstract: 3-Carboxyisocoumarins, 2-thiaisocoumarins and related isocarbostyrils are useful anti-allergic agents. Several of these compounds are novel, and a process for their preparation is provided.

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Inventors: Buckle, Derek Richard (Redhill, EN)
Cantello, Barrie Christian Charles (Horsham, EN)
Smith, Harry (near Horsham, EN)

Application Number: 510803
Filing Date: 1974-09-30
Publication_date: 1976-08-17
Assignee: Beecham Group Limited (EN)
Primary Class(es): 514/456 514/455, 514/826, 546/141, 548/183, 548/228, 548/253, 549/23, 549/280, 549/287
Other Classes:
US Patent Ref:

3484445	Dec, 1969	Lee et al.	424/283.
3578705	May, 1971	Wendler et al.	260/343.
3652765	Mar, 1972	Ellis et al.	424/283.
3733338	May, 1973	Kimura et al.	424/279.
3864493	Feb, 1975	Cairns et al.	424/283.
3879544	Apr, 1975	Reisner et al.	424/337.
3883653	May, 1975	Barth	424/251.
3885038	May, 1975	Pfister et al.	424/283.

Other Refs: Other References: Physician's Desk Reference (PDR) 1974, pp. 760-761.
Molho et al. Chemical Abstracts 67:116789b (1967).
Aknin et al. Chemical Abstracts 67:73483c (1967).