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Title:
6.beta.,17-Dihydroxy-7.alpha.-(lower alkoxy)carbonyl-3-oxo-17.alpha.-pregn-4-ene-21-carboxylic acid .gamma.-lactones and congeners
Abstract:
The preparation and valuable biological properties - especially diuretic activity - of 6.beta.,17-dihydroxy-7.alpha.-(lower alkoxy)carbonyl-3-oxo-17.alpha.-pregn-4-ene-21-carboxylic acid .gamma.-lactones and the corresponding hydroxy acids and salts thereof are disclosed.
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Inventors:
Karim, Aziz (Niles, IL, US) Marsheck, William J. (Harbor Beach, MI, US) Weier, Richard M. (Deerfield, IL, US)
Application Number:
615412
Filing Date: 1975-09-22 Publication_date: 1976-08-03 Assignee:
G. D. Searle & Co. (Chicago, IL)
Primary Class(es):
540/44
435/58, 435/911, 552/509, 552/615
Other Classes:
US Patent Ref:
| 3900467 | Aug, 1975 | Irmscher et al. | 260/239. |
Other Refs:
Primary Examiner:
Roberts, Elbert L.
Assistant Examiner:
Attorney:
Cowley; Barbara L.
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