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Primary Examiner: Drezin, Norman A.
Assistant Examiner:
Attorney: Keps; Joan S., Foggio; Richard D., Edgerton; William H.

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Title: Method of inhibiting histamine activity with guanidine compounds

Abstract: A method of inhibiting histamine activity in particular inhibiting H-2 histamine receptors, by administering heterocyclicalkylguanidines.


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Inventors: Black, James Whyte (Hemel Hempstead, EN)
Durant, Graham John (Welwyn Garden City, EN)
Emmett, John Colin (Codicote, EN)
Ganellin, Charon Robin (Welwyn Garden City, EN)

Application Number: 526767
Filing Date: 1974-11-25
Publication_date: 1976-07-06
Assignee: Smith Kline & French Laboratories Limited (Welwyn Garden City, EN)
Primary Class(es): 514/357 514/341, 514/351, 514/352
Other Classes:
US Patent Ref:
2928829Mar, 1960Mull260/295.
3036083May, 1962Mull260/295.
3278542Oct, 1966Wollweber et al.260/295.
3354174Nov, 1967Bell260/309.

Other Refs: Other References: Derwent Pharmdoc. 586095-B Abstracting Belgian Patent No. 763744, published 3-9-71.