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Title: Benzoxazole derivatives as therapeutics

Abstract: The invention provides novel 5- and 6-benzoxazolyl alkanoic acids, optionally substituted in the 2-position, and derivatives thereof which possess anti-inflammatory, anti-pyretic and analgesic activity. Also provided is a process for preparing such compounds by cyclising an appropriately substituted o-aminophenol and, if necessary, converting the resultant benzoxazole to the desired compound.


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Inventors: Evans, Delme (Chalfont St. Peter, EN)
Dunwell, David William (Camberley, EN)
Hicks, Terence Alan (Farnborough, EN)

Application Number: 587562
Filing Date: 1975-06-17
Publication_date: 1976-06-08
Assignee: Lilly Industries, Ltd. (London, EN)
Primary Class(es): 514/375 514/254.02, 514/338
Other Classes:
US Patent Ref:
3136773Jun, 1964Maeder et a.260/307.

Other Refs:
Primary Examiner: Friedman, Stanley J.
Assistant Examiner:
Attorney: Rowe; James L., Smith; Everet F.