Title: Structured bioerodible drug delivery device

Abstract: A drug delivery device for the continuous and controlled administration of a predetermined therapeutically effective dosage of eye drug to the eye of a mamallian patient over a prolonged period of time. The device meters the flow of polylactic acid polymer micro-encapsulated eye drug by means of a drug release rate controlling material comprised of an anionic polyvalent metal cation cross-linked polyelectrolyte. The device bioerodes in the biological environment of the patient concurrently with the dispensing or at a point in time after the dispensing of the therapeutically desired amount of drug.

Do you think this is a good invention? Vote now:

Votes so far: For:(0) Against:(0)
Other info:

Inventors: Michaels, Alan S. (Atherton, CA, US)

Application Number: 517982
Filing Date: 1974-10-25
Publication_date: 1976-06-08
Assignee: Alza Corporation (Palo Alto, CA)
Primary Class(es): 424/473 424/469, 424/480, 424/481
Other Classes:
US Patent Ref:

3640741	Feb, 1972	Etes	106/170.
3755558	Aug, 1973	Scribner	424/47.
3773919	Nov, 1973	Boswell et al.	424/19.
3826258	Jul, 1974	Abraham	128/260.

Other Refs:
Primary Examiner: Rose, Shep K.
Assistant Examiner:
Attorney: Sabatine; Paul L.