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Primary Examiner: Rose, Shep K.
Assistant Examiner:
Attorney: Merriam, Marshall, Shapiro & Klose

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Title: Oral drug preparations

Abstract: Oral drug preparations are described, having a protracted effect and a suitable rate of release of the drug during its period of action, said preparations comprising a pharmaceutically active component to which has been admixed one or more buffers, and possibly other pharmaceutically acceptable adjuvants, the mixture having been shaped into small particles and subsequently been coated with a film-forming material allowing for diffusion of stomach juice and intestinal juice together with the drugs dissolved therein, but not being soluble in the said juices.

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Inventors: Pedersen, Arne Martinus (Vanlose, DK)

Application Number: 608230
Filing Date: 1975-08-27
Publication_date: 1976-05-04
Assignee: A/S Alfred Benzon (Copenhagen, DK)
Primary Class(es): 424/497
Other Classes:
US Patent Ref:

2971889	Feb, 1961	Swintosky	424/31.
3247066	Apr, 1966	Milosovich	424/21.
3538214	Nov, 1970	Polli et al.	424/19.
3577512	May, 1971	Shepherd et al.	424/21.
3608063	Sep, 1971	Banker	424/22.
3629393	Dec, 1971	Nakamoto et al.	424/22.
3641237	Sep, 1972	Gould et al.	424/16.
3689634	Sep, 1972	Kliment et al.	424/21.
3775537	Nov, 1973	Lehmann et al.	424/21.

Other Refs: Other References: Lehmann, K. Pharm. Ind. 29(6): 396-398 (1967) Acrylic Resin Lacquers for Preparation of Depot Medicinal Forms.
Lehmann, K. et al. Pharm. Ind. 31(5): 319-322 (1969) Permeable Acrylic Resin Lacquers for Production of Medicinal Depot Forms II. (1).
Lehmann, K. et al. Pharm. Ind. 31(6): 409-412 (1969) Permeable Acrylic Resin Lacquers for Production of Medicinal Depot Forms II. (2).
Lehmann, K. et al. Drugs Made Ger. 16(4): 126, 131-132, 134, 136 (1973) Use of Aqueous Synthetic-Polymer Dispersions for Coating Pharmaceutical Dosage Forms.
Lehmann, K. et al. Labo-Pharma-Probl. Tech. 22 (228): 57-62, 65 (1974) Use of Aqueous Plastic Dispersions for Coating Pharmaceutical Forms.
Lehmann, K. Mfg. Chem. Aerosol News. 45(5): 48, 50 (1974) Polymer Coating of tablets. Versatile Technique.