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Title:
Process of stabilizing therapeutically useful plasmin solutions
Abstract:
Plasmin compositions containing a concentration of plasmin sufficiently great for therapeutic administration are stabilized by the addition thereto of a physiologically nontoxic amino acid. This application is a continuation of application Ser. No. 519,809 filed Dec. 3, 1969, which is a continuation-in-part of application Ser. No. 189,367 filed Apr. 23, 1962 both now abandoned.
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Inventors:
Jensen, Villy Johannes (Copenhagen Vanlose, DK)
Application Number:
860172
Filing Date: 1969-09-19 Publication_date: 1976-04-13 Assignee:
Novo Terapeutisk Laboratorium A/S (DK)
Primary Class(es):
424/94.3
424/94.64, 435/188, 435/217
Other Classes:
US Patent Ref:
| 3051627 | Aug, 1962 | Bradford et al. | 424/94. | | 3066079 | Nov, 1962 | Hagen et al. | 195/66. | | 3434929 | Mar, 1969 | Buck et al. | 195/66. |
Other Refs:
Other References:
Alkjaersig et al, J. Biol. Chem., Vol. 234, No. 4, pp. 832-837, Apr. 1959. Cliffton, Annals of the New York Academy of Science, Vol. 68, Art. 1, pp. 209-210, Aug. 30, 1957. Igawa et al, Keio J. Medicine, Vol. 8, No. 4, 225-233, Dec. 1959. Storm et al, Acta Chir. Scand, suppl., Vol. 283, pp. 315-321, 1961. |