Title: Method and apparatus for continuous mixing of blood plasma and additives

Abstract: A method and apparatus for continuous mixing of blood plasma with additives, such as alcohol, comprises an elongated cylindrical chamber with inner and outer coolant chambers disposed adjacent thereto with an intermediate product chamber containing an impeller. Plasma and at least one additive are introduced into the product chamber in the vicinity of the impeller which mixes the blood plasma and additives. The blood plasma and additives then flow through the product chamber where they are cooled by a refrigerant flowing in the inner and outer cooling chambers. The mixed and cooled blood plasma and additives then flow from an outlet in the product chamber. A method is disclosed of continuously supplying a flow of blood plasma and desired additives in predetermined proportions and mixing and cooling the continuous flow of the combined blood plasma and additives.

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Inventors: Mason, William H. (Woodbridge, CT, US)

Application Number: 523533
Filing Date: 1974-11-13
Publication_date: 1976-03-02
Assignee: The United States of America as represented by the Department of Health, (Washington, DC)
Primary Class(es): 366/149 62/392, 62/396, 165/141, 366/160.3, 422/44, 422/111, 607/106
Other Classes:
US Patent Ref:

2375558	May, 1945	Hutchinson	259/23.
2396235	Mar, 1946	Arvins	165/141.
2541069	Feb, 1951	Jones	165/140.
2845929	Aug, 1958	Strumia	128/400.
2876769	Mar, 1959	Cordova	128/400.
3256883	Jun, 1966	Wall	128/400.
3280899	Oct, 1966	Brasie	165/109.
3332468	Jul, 1967	Dietze	159/2.
3620684	Nov, 1971	Brooks	23/285.
3731731	May, 1973	Bach et al.	165/154.
3764271	Oct, 1973	Brumfield	128/400.
3807958	Apr, 1974	Brumfield	128/400.

Other Refs:
Primary Examiner: Jenkins, Robert W.
Assistant Examiner:
Attorney: Browdy and Neimark