Title: Process for preparing rifamycin S by hydrolysis of rifamycin O

Abstract: A process for preparing rifamycin S from rifamycin O. Rifamycin O is dissolved in a mixture of an organic solvent and an alcohol at room temperature. The rifamycin O is then hydrolyzed with a mineral acid and the thus obtained rifamycin S is purified by crystallization.

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Inventors: Pasqualucci, Carmine (Milan, IT)
Scarpitta, Giuseppe (Pavia, IT)
Bonfanti, Giovanni (Milan, IT)

Application Number: 517834
Filing Date: 1974-10-24
Publication_date: 1976-01-20
Assignee: Archifar Industrie Chimiche Del Trentino S.p.A. (Rovereto, IT)
Primary Class(es): 540/458
Other Classes:
US Patent Ref:
Other Refs: 924,472

Apr, 1963	UK

Primary Examiner: Jiles, Henry R.
Assistant Examiner: Bond, Robert T.
Attorney: Waters, Schwartz & Nissen