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Primary Examiner: Moyer, Donald B.
Assistant Examiner:
Attorney: Bierman; Jordan B., Bierman; Linda G., Stempler; Kenneth J.

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Title: Novel azabicyclo octane derivative and process for preparing same

Abstract: A compound of the formula: ##SPC1## Wherein R.sup.1 is hydrogen, phenyl, alkyl of one to five carbon atoms, cycloalkyl of three to four carbon atoms, or alkyl of one to five carbon atoms having a substituent selected from the group consisting of phenyl, benzoyl and 4-fluorobenzoyl, R.sup.2 is hydrogen or alkyl of one to three carbon atoms, and R.sup.3 is hydrogen, alkanoyl of two to six carbon atoms, benzoyl or nicotinoyl, is disclosed. Several methods for preparing the compound (I) is also disclosed. The compound (I) and a pharmaceutically acceptable acid addition salt thereof are useful as analgesic agents.


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Inventors: Takeda, Mikio (Urawa, JA)
Inoue, Hirozumi (Kawaguichi, JA)
Hayashi, Goro (Toyonaka, JA)
Nurimoto, Seiichi (Toyonaka, JA)

Application Number: 486988
Filing Date: 1974-07-10
Publication_date: 1976-01-13
Assignee: Tanabe Seiyaku Co., Ltd (Osaka, JA)
Primary Class(es): 546/276.7 548/452, 548/512
Other Classes:
US Patent Ref:
3600400Aug, 1971Schenker260/326.

Other Refs: 952,137
Mar, 1964UK
Other References: Chemical Abstracts Vol. 76:14312j (1972).