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Primary Examiner: Morgenstern, Norman
Assistant Examiner:
Attorney: Welt; Samuel L., Saxe; Jon S., Wittekind; Raymond R.

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Title: Synthesis of 2-alkyl-cyclopentan-1,3-diones

Abstract: 2-Lower alkyl-cyclopentan-1,3-diones are prepared in high yield by cyclization of gamma-ketoesters in the presence of a colloidal suspension of an alkali metal primary lower alcoholate.

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Inventors: Hengartner, Urs Oskar (Montclair, NJ, US)
Wehrli, Pius Anton (North Caldwell, NJ, US)

Application Number: 436579
Filing Date: 1974-01-25
Publication_date: 1976-01-06
Assignee: Hoffmann-La Roche Inc. (Nutley, NJ)
Primary Class(es): 568/346 560/174, 568/379
Other Classes:
US Patent Ref:

2158071	May, 1939	Hansley	260/586.
3349130	Oct, 1967	Bucourt et al.	260/586.
3504036	Mar, 1970	Schick et al.	260/586.
3518296	Jun, 1970	Bucourt et al.	260/586.
3798259	Mar, 1974	Wehrli	260/586.

Other Refs: Other References: crown Zellerbach, "Dimethyl Sulfoxide, Reaction Medium and Reactant," p. 1, (1962).