Home

Primary Examiner: Todd, G. Thomas
Assistant Examiner:
Attorney: Welt; Samuel L., Leon; Bernard S., Isgro; William G.

Next ten patents ordered by date:

Substituted piperidines
Phosphinolines and phosphindolines
Substituted piperidine derivatives
2-Amino-5-spiro substituted oxazoline-4-one compounds
Benzopyrano and benzothiopyrano [2,3-6] pyridines
Substituted pyridinylalkoxy-, pyridinylalkylsulfonyl- and pyridinylalkylthio- phenylureas
Pyridyl phenyl-carbamate rodenticides
3-Pyridylmethyl aryl urea rodenticides
Thieno[3,4-d]pyrimidines
Substituted alkanoic acids and derivatives

Translate:
En
De
Es
Fr
It
Pt
Ja
Ko
Zh

Title: Quinuclidine derivatives

Abstract: Quinine, quinidine and analogs thereof, are prepared by reacting a 4-quinolyllithium compound with a 4,5-erythro-5-ethyl(or vinyl)-quinuclidine-2 .xi.-carboxaldehyde or the corresponding quinuclidine-2-carboxylic acid alkyl ester. Also described, inter alia, is the preparation of a 4,5-erythro-5-ethyl(or vinyl)-quinuclidine-2 .xi.-carboxaldehyde, and a 4,5-erythro-5-ethyl(or vinyl)-quinuclidine-2 .xi.-carboxylic acid and esters thereof. The end products are useful as anti-malarial and antiarrhythmic agents.

Do you think this is a good invention? Vote now:

Votes so far: For:(0) Against:(0)
Other info:

Inventors: Grethe, Guenter (North Caldwell, NJ, US)
Uskokovic, Milan Radoje (Upper Montclair, NJ, US)

Application Number: 466355
Filing Date: 1974-05-02
Publication_date: 1976-01-06
Assignee: Hoffmann-La Roche Inc. (Nutley, NJ)
Primary Class(es): 546/133
Other Classes:
US Patent Ref:
Other Refs: Other References: chem. Abstracts, 53: 6278c, (1959).
Chem. Abstracts, 54: 22641a, (1960).