Title: Soluble hydrophilic polymers and process for processing the same

Abstract: Soluble, hydrophilic polymers suitable for medical use and as blood plasma substitutes comprising low molecular weight polymer derived from at least one monomer of an acrylamide type material or a mono-ester of an acrylic type acid and a glycol which is condensed with bifunctional compounds to form a condensation polymer having increased molecular weight and enzymatically cleavable cross-links. The hydrophilic polymer is produced by polymerizing the acrylamide type material or monoester mentioned above to form a low molecular weight polymer which is then condensed with a bifunctional compound to form a high molecular weight condensation polymer having enzymatically cleavable cross-links.

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Inventors: Kopecek, Jinrich (Prague, CS)
Vacik, Jiri (Prague, CS)
Sprincl, Ladislav (Prague-Stodulky, CS)

Application Number: 335748
Filing Date: 1973-02-26
Publication_date: 1976-01-06
Assignee: Ceskoslovenska akadamie ved (Prague, CS)
Primary Class(es): 525/123 424/78.18, 525/142, 525/154, 525/162, 525/163, 525/328.2, 525/328.4, 525/328.8, 525/328.9, 525/329.5, 525/359.3, 525/375, 525/385, 525/386, 525/937, 526/260,
Other Classes:
US Patent Ref:

3245941	Apr, 1966	Mayer et al.	260/77.
3326823	Jun, 1967	Landler et al.	260/2.
3382090	May, 1968	Meisel et al.	260/2.
3575946	Apr, 1971	Chromecek et al.	260/29.
3577522	May, 1971	Hymes	424/78.
3590125	Jun, 1971	Hymes	424/78.
3607848	Sep, 1971	Stoy et al.	424/81.
3787474	Jan, 1974	Daniels et al.	424/78.
R27151	Jun, 1971	Hicks	260/77.

Other Refs: 802,740

Oct, 1958	UK

Other References: Saunders et al., Polyurethanes Part I., Interscience, New York, (1962), pp. 111, 338.